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XELJANZ may help reduce RA pain and swelling in the joints, and it has also been shown to help reduce the progression of joint damage. XELJANZ, the first FDA-approved JAK inhibitor, may work differently to treat your moderate to severe RA.

Your doctor may have prescribed XELJANZ if 1 or more tumor necrosis factor (TNF) blockers have been used and did not work well or cannot be tolerated.

XELJANZ may cause serious side effects. Learn more about the Most Important Risk Information you should know about XELJANZ.